There are hundreds of open source CMS, at least a dozen of which are excellent, and targeted to slightly different flavors of audience. There is one site which allows you to demo at least 100 of them, but I can't remember the URL.
Here is another good starting point in sorting through the great variety:
http://www.cmsreview.com/
Specifically in OS CRM, the lead is probably Sugar:
http://www.sugarcrm.com/crm/demo/sugar-suite.html
These demos will give you a solid intro to what you need to know. Note that Sugar is upper-end OS, and has a 'professional' flavor which costs money, so you may want to look closely at the fine print if need be.
-Jared